产品货号：
Z31193
中文名称：
Dystrophin/DMD抗体
英文名称：
Anti-Dystrophin/DMD Antibody (Clone#MANDYS8)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Dystrophin/DMD Antibody (Clone#MANDYS8) |
| 指标别名 | BMD;CMD3B;DMD;DXS142;DXS164;DXS206;DXS230;DXS239;DXS268;DXS269;DXS270;DXS272;dystrophin |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat,rabbit |
| 应用范围 | WB,IHC |
| 基因名称 | DMD |
| 克隆号 | MANDYS8 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | Recombinant human dystrophin fragment. |
| 实际分子量 | 426KD |
| 成分 | 200μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Ascites |
| 浓度 | 200μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Dystrophin(DMD) gene has 79 exons spanning at least 2,300kb(2.3 Mb).The C terminus of the dystrophin protein is encoded by a highly conserved,alternatively spliced region of the gene.beta-dystroglycan binding activity is expressed by the dystrophin fragment spanning amino acids 3026-3345 containing the ZZ domain.DMD transcript is formed by at least 60 exons;the first half of the transcript is formed by a minimum of 33 exons spanning nearly 1000kb,and the remaining portion has at least 27 exons that may spread over a similar distance.Dystrophin gene is expressed at a higher level in primary cultures of neuronal cells than in astro-glial cells derived from adult mouse brain.overexpression of dystrophin prevents the development of the abnormal mechanical properties associated with dystrophic muscle without causing deleterious side effects. |
| Uniprot ID | P11532 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | dystrophin |
| 蛋白名全称 | Dystrophin |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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